Mario Segale, Developer Who Inspired Nintendo to Name Super Mario

Penicillin was discovered by Alexander Fleming, but he never attempted to turn it into an antibiotic. It wasn't until ten years later that Howard Florey discovered Fleming's obscure paper and understood the mold's potential. Up to 200 million lives may have been saved as a result of Florey's work.

David Vetter lived his whole 12 years in sterile “bubble”. He was “outside” for 20 second after being removed from his mother’s womb. He never touched any human.

Josephine Myrtle Corbin, an American sideshow performer born in 1868, had a rare condition known as dipygus, which caused her to have four legs, each smaller inner leg paired with one of her outer legs. Corbin joined the sideshow circuit, captivating audiences as the "Four-Legged Girl from Texas."

This clay tablet, written in cuneiform, is the oldest known written customer complaint about the delivery of poor quality copper ingots. Originally from ancient Babylon, the tablet dates back to 1750 BCE, and it was written by a customer named Nanni to a merchant named Ea-Nasir. It is currently housed in the British Museum.

In 1814, there was a beer flood in London when a tank containing more than 300,000 gallons ruptured in which 8 people drowned.

Vince Coleman, a railway dispatcher, sacrificed his life in order to warn an incoming train of an imminent explosion. His telegraph said “Hold up the train. Ammunition ship afire in harbor making for Pier 6 and will explode. Guess this will be my last message. Good-bye, boys.” He saved 300 lives.

In 1887, Susanna Salter became the first female mayor in the United States, elected in Argonia, Kansas. Her nomination was initially a prank by men opposing women in politics. However, she won by a landslide and served effectively, inspiring the women’s suffrage movement and breaking barriers for women in leadership.

1850 Dmitri Mendeleev walked almost a thousand miles to Moscow so he could apply for the University of Moscow. Although he was not accepted, he walked to St. Petersburg where he was accepted, And with that education, he developed the the periodic table of the elements

Martin Couney never qualified as a medical doctor. However, in the 1900s, he saved thousands of premature babies by exhibiting them in incubators at his Coney Island sideshow. Over the course of his career, he is said to have saved about 6,500 babies that had previously been written off by mainstream medicine.

Before alarm clocks were invented, there was a profession called a knocker-up, which involved going from client to client and tapping on their windows (or banging on their doors) with long sticks until they were awake. It lasted into the 1920s.

Blanche Monnier, she was a French woman noted for her beauty, she wished to marry an old lawyer that her mother disapproved of, so she locked her in a small dark room in her attic for 25 years.

The 18th century marked a turning point in the quest for women’s rights, as passionate voices challenged centuries of gender inequality and laid the groundwork for modern feminism. From pioneers like Mary Wollstonecraft to revolutionary declarations and early advocacy, this era sparked debates on education, political participation, and social justice that continue to resonate today. Journey through the origins of women’s rights movements and discover how their bold ideas shaped the fight for equality.

American environmental activist Julia “Butterfly” Hill lived in a 1500-year-old California Redwood tree for 738 days to prevent it from being cut down by the Pacific Lumber Company. The Simpson’s episode “Lisa the Tree Hugger” was inspired by Hill’s story.

On April 28, 1988, Aloha Airlines flight 243 was on the way to Honolulu from Hilo when a huge portion of the upper part of the fuselage blew off the airplane.

Before women were allowed to run in the Boston Marathon, Kathrine Switzer participated. A race official attempted to forcefully remove her from the race in 1967, but her boyfriend pushed him down. She was the first female finisher who had a numbered entry in the race.

The inventor of shopping carts, Sylvan Goldman, had to hire several male and female models to push carts around in his store, demonstrate their utility, and explain their use to other customers, due to not catching on initially.

In the 1980s, an Indian man spent 72 hours in a glass cabin with 72 snakes, some of which were extremely venomous. His aim was to prove that snakes only attack when provoked. Remarkably, he was not bitten once in those 72 hours and even set a Guinness World Record in the process.

Richard Jewell, an American security guard, discovered a bomb during the 1996 Olympic Games in Atlanta and assisted in the evacuation, but was later wrongfully accused and faced public scrutiny. He was cleared, but it had a lasting impact on him until his death in 2007 at the age of 44.

At the 1936 Summer Olympics, two Japanese pole vaulters named Sueo Oe and Shuhei Nishida tied for second, but they declined to compete against each other. As a result, Nishida was awarded the silver medal and Oe won a bronze medal. Upon returning to Japan, the athletes had their medals cut in half and spliced together to create new "friendship medals," which were half silver and half bronze.

Anne Oakley was such a good shooter that she could split a playing card help edge-on, hit dimes thrown into the air, shoot cigarette from her husband's lips, and pierce a playing card thrown into the air before it hit the ground.

A 2,000-year-old mummy of a Chinese woman, Xin Zhui, also known as “Lady Dai,” was preserved in 21 gallons of an “unknown liquid.” With her original hair, organs, eyebrows, and eyelashes intact, the mummy still has blood in her veins. Her skin and ligaments are soft and as flexible as that of a living person.

Wrigley's was originally a soap company that gifted baking powder with their soap. The baking powder became more popular than the soap so they switched to selling baking powder with chewing gum as a gift. The gum became more popular than the baking powder so the company switched to selling gum.

Marion Stokes, a Philadelphia woman began taping whatever was on television in 1979 and didn’t stop until her death in 2012. The 71,000 VHS and Betamax tapes she made are the most complete collection preserving this era of TV. They are being digitized by the Internet Archive.

After the death of her husband, Mary Ann Bevan had no income to support herself and her children. She then decided to enter a contest where she won the title of “ugliest woman” and was later hired by a circus. She endured this ridicule from the world to provide for her family.

The first person to jump off the Brooklyn Bridge was a professional high diver who "wanted to demonstrate that people did not die simply by falling through the air, thus encouraging people to be willing to jump from a burning building into a net." He proved himself correct by safely falling 135 feet through the air and dying only when he hit the water.